하악골에 발생한 중심성 과립세포 치성종양
Central Granular Cell Odontogenic Tumor of the Mandible
윤혜정, 최소영, 홍성두, 홍삼표, 이재일,
소속 상세정보
윤혜정 ( Yoon Hye-Jung ) - 서울대학교 치의학대학원 구강병리학교실
최소영 ( Choi So-Young ) - 서울대학교 치의학대학원 구강병리학교실
홍성두 ( Hong Seong-Doo ) - 서울대학교 치의학대학원 구강병리학교실
홍삼표 ( Hong Sam-Pyo ) - 서울대학교 치의학대학원 구강병리학교실
이재일 ( Lee Jae-Il ) - 서울대학교 치의학대학원 구강병리학교실
KMID : 0829220110350020095
Abstract
Central granular cell odontogenic tumor (CGCOT) is a rare benign odontogenic neoplasm, with approximately 30 cases having been reported. The pathogenesis of CGCOT as well as the designation of this lesion is controversial because of unknown histogenesis of the granular cell. We present an additional case of CGCOT involving the mandible of a 50-year-old Korean man who complained of asymptomatic swelling of the right buccal gingiva. Current lesion is microscopically characterized by densely packed polyhedral granular cells surrounding interspersed islands or strands of odontogenic epithelium. Immunohistochemically, granular cells were positive for Vimentin and CD68, and negative for cytokeratin and S-100. These features support a mesenchymal origin for the granular cells as other results previously reported.
키워드
Central granular cell odontogenic tumor; Mandible
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